Antigen Record Ag003611

AgACCAg003611
Date19-08-2008
Last updated14-12-2016
Antigen NameWT1
Full NameWilms tumor 1
SynonymWilms' tumor protein; GUD; WAGR; WIT-2; WT33; WT1

another display format
  • Wilms' tumor protein
  • GUD
  • WAGR
  • WIT-2
  • WT33
  • WT1
UniProt IDP19544
NCBI Gene ID7490
GeneCard IDGC11M032365
SwissProt VARIANT IDVAR_007751
CommentDenys-Drash syndrome (DDS) - Defects in WT1 are the cause of Denys-Drash syndrome. DDS is a typical nephropathy characterized by diffuse mesangial sclerosis, genital abnormalities, and/or Wilms tumor. There is phenotypic overlap with WAGR syndrome and Frasier syndrome. Inheritance is autosomal dominant, but most cases are sporadic. Isolated diffuse mesangial sclerosis (IDMS) - Defects in WT1 are the cause of isolated diffuse mesangial sclerosis. IDMS is an early-onset nephrotic syndrome occurring in the absence of other abnormalities and resulting in renal failure. Inheritance is autosomal recessive
AnnotationThis is a fragment sequence.
IsoformsAg000203,  Ag000204,  Ag000205,  Ag000206,  Ag000207,  Ag001874,  Ag001875,  Ag001876

Alignment of all Isoforms
Mutation entriesAg001542,  Ag001543,  Ag001544,  Ag001545,  Ag001546,  Ag001547,  Ag001548,  Ag001549,  Ag001550,  Ag001551,  Ag001552,  Ag001553,  Ag001554,  Ag001555,  Ag001556,  Ag001557
... Display all entries


View mutation map
RNA/protein expression profileRNA and protein Expression profile
Predicted HLA binders
Allele:  predictions
Peptide length:   
Reference sequenceRHTGVKPFQCKTCQRKFSRSDHLKTHTRTHTGKTSEKPFSC
Antigen sequenceRHTGVKPFQCKTCQRKFSRSNHLKTHTRTHTGKTSEKPFSC