Antigen Record Ag000433

AgACC	Ag000433
Date	01-22-2008
Last updated	14-12-2016
Antigen Name	APC
Full Name	Adenomatosis polyposis coli
Synonym	DP2; DP2.5; DP3; FAP; FPC; GS; Adenomatous polyposis coli protein; Protein APC; adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor another display format DP2 DP2.5 DP3 FAP FPC GS Adenomatous polyposis coli protein Protein APC adenomatosis polyposis coli adenomatosis polyposis coli tumor suppressor
UniProt ID	P25054
NCBI Gene ID	324
GeneCard ID	GC05P112707
Comment	This is a splice isoform.
Annotation	This is a full length sequence.
Isoforms	Ag000432 Alignment of all Isoforms
Mutation entries	Ag000656, Ag000657, Ag000658, Ag000659, Ag000660, Ag000661, Ag000662, Ag000663, Ag000664, Ag000665, Ag000666, Ag000667, Ag000668, Ag000669, Ag000670, Ag000671 ... Display all entries Ag000673, Ag000674, Ag000675, Ag000676, Ag000677, Ag000678, Ag000679, Ag000680, Ag000681, Ag000682, Ag000683, Ag000684, Ag000685, Ag000686, Ag000687, Ag000688, Ag000689, Ag000690, Ag000691, Ag000692, Ag000693, Ag000694, Ag000695, Ag000696, Ag000697, Ag000698, Ag000699, Ag000700, Ag000701, Ag000702, Ag000703, Ag000704, Ag000705, Ag000706, Ag000707, Ag000708, Ag000709, Ag000710, Ag000711, Ag000712, Ag000713, Ag000714, Ag000715, Ag000716, Ag000717, Ag000718, Ag000719, Ag000720, Ag000721, Ag000722, Ag000723, Ag000724, Ag000725, Ag000726, Ag000727, Ag000728, Ag000729, Ag000730, Ag000731, Ag000732, Ag000733, Ag000734, Ag000735, Ag000736, Ag000737, Ag004069, Ag004070, Ag004071, Ag004072, Ag004073, Ag004074, Ag004075, Ag004076, Ag004077, Ag004078, Ag004079, Ag004080, Ag004081, Ag004082, Ag004083, Ag004084, Ag004085, Ag004086, Ag004087, Ag004088, Ag004089, Ag004090 View mutation map
RNA/protein expression profile	RNA and protein Expression profile
T cell epitope	Epitope sequence	Position	HLA allele	Reference
	KIMDQVQQA	1644-1652	A2	12750359
HLA ligand	Ligand Sequence	Position	HLA allele	Reference
	KIMDQVQQA	1644-1652	A2	12750359
Predicted HLA binders	Allele: predictions Peptide length:
Antigen sequence	MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAMASSGQIDLLE RLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRGFVNGSRESTGYLEELEKE RSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDM EKRAQRRIARIQQIEKDILRIRQLLQSQATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGS TTRMDHETASVLSSSSTHSAPRRLTSHLGTKIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVC VLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCS MKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSA LWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNC LQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMGSAAALRNLMA NRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVF DTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSLDSSRSEKDRSLERERGIGLGNYHPATENPG TSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAAHTHSNTYNFTKSE NSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSA NHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWARPKHIIEDEIKQSEQRQSRNQSTTYPVYTES TDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHGINQNVSQSLCQEDDYEDDKPTNYSERYSEEE QHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSSQKQSFSFSKSSSGQSSKTEHMSSSSENTSTP SSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQTYCVEDTPICFSRCSSLSSLSSAEDEIGCNQ TTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHPRTKSSRLQGSSLSSESARHKAVEFSSGAKSP SKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTM PPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQAAVNAAVQRVQVLPDADTLLHFATESTPDGFS CSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDD IEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPSQLPVYKLLPSQNRLQPQKHVSFTPGDDMPRV YCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQSGEFEKRDTIPTEGRSTDEAQGGKTSSVTIP ELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQVQQASASSSAPNKNQLDGKKKKPTSPVKPIPQ NTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNSKVFNDKLPNNEDRVRGSFAFDSPHHYTPIEG TPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKESEAKVTSHTELTSNQQSANKTQAIAKQPINRG QPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTPVCFSHNSSLSSLSDIDQENNNKENEPIKETE PPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQECISSAMPKKKKPSRLKGDNE KHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANSIVSSLHQAAAAACLSRQASSD SDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKVYKSLITG KVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSP RGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQPLSRPIQSPGRNSISPGRNGISPPNK LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGLNQMNNGNGAN KKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSPTLRRKLEESASFESLSPSSRPASPTRSQAQT PVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKREH SKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEKHVNSISGTKQSKENQVSAKGTWRKIKENEFS PTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKAN PNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAPDQKGTEIKPGQNNPVPVSETNESSIVERTP FSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSP KRHSGSYLVTSV