Antigen Record Ag000432

AgACC	Ag000432
Date	01-22-2008
Last updated	14-12-2016
Antigen Name	APC
Full Name	Adenomatosis polyposis coli
Synonym	DP2; DP2.5; DP3; FAP; FPC; GS; Adenomatous polyposis coli protein; Protein APC; adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor another display format DP2 DP2.5 DP3 FAP FPC GS Adenomatous polyposis coli protein Protein APC adenomatosis polyposis coli adenomatosis polyposis coli tumor suppressor
UniProt ID	P25054
NCBI Gene ID	324
GeneCard ID	GC05P112707
Comment	This is a splice isoform.
Annotation	This is a full length sequence.
Isoforms	Ag000433 Alignment of all Isoforms
Mutation entries	Ag000656, Ag000657, Ag000658, Ag000659, Ag000660, Ag000661, Ag000662, Ag000663, Ag000664, Ag000665, Ag000666, Ag000667, Ag000668, Ag000669, Ag000670, Ag000671 ... Display all entries Ag000673, Ag000674, Ag000675, Ag000676, Ag000677, Ag000678, Ag000679, Ag000680, Ag000681, Ag000682, Ag000683, Ag000684, Ag000685, Ag000686, Ag000687, Ag000688, Ag000689, Ag000690, Ag000691, Ag000692, Ag000693, Ag000694, Ag000695, Ag000696, Ag000697, Ag000698, Ag000699, Ag000700, Ag000701, Ag000702, Ag000703, Ag000704, Ag000705, Ag000706, Ag000707, Ag000708, Ag000709, Ag000710, Ag000711, Ag000712, Ag000713, Ag000714, Ag000715, Ag000716, Ag000717, Ag000718, Ag000719, Ag000720, Ag000721, Ag000722, Ag000723, Ag000724, Ag000725, Ag000726, Ag000727, Ag000728, Ag000729, Ag000730, Ag000731, Ag000732, Ag000733, Ag000734, Ag000735, Ag000736, Ag000737, Ag004069, Ag004070, Ag004071, Ag004072, Ag004073, Ag004074, Ag004075, Ag004076, Ag004077, Ag004078, Ag004079, Ag004080, Ag004081, Ag004082, Ag004083, Ag004084, Ag004085, Ag004086, Ag004087, Ag004088, Ag004089, Ag004090 View mutation map
RNA/protein expression profile	RNA and protein Expression profile
T cell epitope	Epitope sequence	Position	HLA allele	Reference
	KIMDQVQQA	1745-1753	A2	12750359
HLA ligand	Ligand Sequence	Position	HLA allele	Reference
	KIMDQVQQA	1745-1753	A2	12750359
Predicted HLA binders	Allele: predictions Peptide length:
Antigen sequence	MAAASYDQLLKQVEALKMENSNLRQELEDNSNHLTKLETEASNMKEVLKQLQGSIEDEAMASSGQIDLLE RLKELNLDSSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRRGFVNGSRESTGYLEELEKE RSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQTDMTRRQLEYEARQIRVAMEEQLGTCQDM EKRAQRRIARIQQIEKDILRIRQLLQSQATEAERSSQNKHETGSHDAERQNEGQGVGEINMATSGNGQGS TTRMDHETASVLSSSSTHSAPRRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQS GCLPLLIQLLHGNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETC WEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQVDCEMYGLTN DHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSK KTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLA IIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWD MGAVSMLKNLIHSKHKMIAMGSAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLS ETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRHDDNRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGS LDSSRSEKDRSLERERGIGLGNYHPATENPGTSSKRGLQISTTAAQIAKVMEEVSAIHTSQEDRSSGSTT ELHCVTDERNALRRSSAAHTHSNTYNFTKSENSNRTCSMPYAKLEYKRSSNDSLNSVSSSDGYGKRGQMK PSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGELDTPINYSLKYSDEQLNSGRQSPSQNERWA RPKHIIEDEIKQSEQRQSRNQSTTYPVYTESTDDKHLKFQPHFGQQECVSPYRSRGANGSETNRVGSNHG INQNVSQSLCQEDDYEDDKPTNYSERYSEEEQHEEEERPTNYSIKYNEEKRHVDQPIDYSLKYATDIPSS QKQSFSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSGQPQKAATCKVSSINQETIQ TYCVEDTPICFSRCSSLSSLSSAEDEIGCNQTTQEADSANTLQIAEIKEKIGTRSAEDPVSEVPAVSQHP RTKSSRLQGSSLSSESARHKAVEFSSGAKSPSKSGAQTPKSPPEHYVQETPLMFSRCTSVSSLDSFESRS IASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPPPPPQTAQTKREVPKNKAPTAEKRESGPKQA AVNAAVQRVQVLPDADTLLHFATESTPDGFSCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESE QPKESNENQEKEAEKTIDSEKDLLDDSDDDDIEILEECIISAMPTKSSRKAKKPAQTASKLPPPVARKPS QLPVYKLLPSQNRLQPQKHVSFTPGDDMPRVYCVEGTPINFSTATSLSDLTIESPPNELAAGEGVRGGAQ SGEFEKRDTIPTEGRSTDEAQGGKTSSVTIPELDDNKAEEGDILAECINSAMPKGKSHKPFRVKKIMDQV QQASASSSAPNKNQLDGKKKKPTSPVKPIPQNTEYRTRVRKNADSKNNLNAERVFSDNKDSKKQNLKNNS KVFNDKLPNNEDRVRGSFAFDSPHHYTPIEGTPYCFSRNDSLSSLDFDDDDVDLSREKAELRKAKENKES EAKVTSHTELTSNQQSANKTQAIAKQPINRGQPKPILQKQSTFPQSSKDIPDRGAATDEKLQNFAIENTP VCFSHNSSLSSLSDIDQENNNKENEPIKETEPPDSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSL SIDSEDDLLQECISSAMPKKKKPSRLKGDNEKHSPRNMGGILGEDLTLDLKDIQRPDSEHGLSPDSENFD WKAIQEGANSIVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSS SSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPS RPAQQPLSRPIQSPGRNSISPGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTK QTGLSKNASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPNLSPTIEYNDG RPAKRHDIARSHSESPSRLPINRSGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSESSEKAKSEDEK HVNSISGTKQSKENQVSAKGTWRKIKENEFSPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVR IEDCPINNPRSGRSPTGNTPPVIDSVSEKANPNIKDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDA PDQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSA RPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKRHSGSYLVTSV