Antigen Record Ag000002

AgACCAg000002
Date11-02-2007
Last updated14-12-2016
Antigen NameBIRC5
Common NameSurvivin
Full NameBaculoviral IAP repeat-containing protein 5
SynonymSurvivin; Apoptosis inhibitor 4; Apoptosis inhibitor survivin; apoptosis inhibitor 4 (survivin); baculoviral IAP repeat-containing 5; API4; EPR-1; IAP4; SVV5

another display format
  • Survivin
  • Apoptosis inhibitor 4
  • Apoptosis inhibitor survivin
  • apoptosis inhibitor 4 (survivin)
  • baculoviral IAP repeat-containing 5
  • API4
  • EPR-1
  • IAP4
  • SVV5
UniProt IDO15392
NCBI Gene ID332
GeneCard IDGC17P078214
CommentThis sequence is a splice isoform and it was reported to be expressed in lymphoma, lung cancer, colon cancer, pancreas cancer, prostate cancer and breast cancer (9256286).
AnnotationThis is a full length sequence.
IsoformsAg000003,  Ag000004,  Ag000005,  Ag000006,  Ag000007,  Ag000008

Alignment of all Isoforms
Mutation entriesAg002182

View mutation map
RNA/protein expression profileRNA and protein Expression profile
T cell epitopeEpitope sequencePositionHLA alleleReference
ELTLGEFLKL95-104 A2  10987296
FLKLDRERA101-109 A2  11221872
TLPPAWQPFL5-14 A2  10987296
HLA ligandLigand SequencePositionHLA alleleReference
AFLSVKKQF85-93 A*2402  15779886
AFLSVKKQF85-93 B*0801  15779886
APTLPPAWQ3-11 B*0702  15779886
CFFCFKELE57-65 A*2402  15779886
CFKELEGWE60-68 B*1501  15779886
CTPERMAEA33-41 A*0201  15779886
DLAQCFFCF53-61 A*2402  15779886
EAGFIHCPT40-48 A*2402  15779886
ELTLGEFLK95-103 A*1101  15779886
EPDLAQCFF51-59 A*2402  15779886
FCFKELEGW59-67 A*0201  15779886
FCFKELEGW59-67 A*2402  15779886
FCFKELEGW59-67 B*1501  15779886
FEELTLGEF93-101 A*2402  15779886
FFCFKELEG58-66 A*2402  15779886
FIHCPTENE43-51 A*0201  15779886
FLKDHRIST13-21 A*0201  15779886
FLKDHRIST13-21 B*0801  15779886
FLKDHRIST13-21 B*1501  15779886
FLKLDRERA101-109 A*0201  15779886
FLKLDRERA101-109 B*0801  15779886
FLSVKKQFE86-94 A*0201  15779886
FLSVKKQFE86-94 B*0801  15779886
GAPTLPPAW2-10 A*2402  15779886
GCAFLSVKK83-91 A*0301  15779886
GCAFLSVKK83-91 A*1101  15779886
HRISTFKNW17-25 A*2402  15779886
HSSGCAFLS80-88 A*0201  15779886
IAKETNNKK113-121 A*0301  15779886
IAKETNNKK113-121 A*1101  15779886
ISTFKNWPF19-27 A*0201  15779886
ISTFKNWPF19-27 A*2402  15779886
ISTFKNWPF19-27 B*1501  15779886
KDHRISTFK15-23 A*0301  15779886
KDHRISTFK15-23 A*1101  15779886
KHSSGCAFL79-87 A*0201  15779886
KHSSGCAFL79-87 A*2402  15779886
KIAKETNNK112-120 A*0301  15779886
KIAKETNNK112-120 A*1101  15779886
KKHSSGCAF78-86 A*2402  15779886
KLDRERAKN103-111 A*0201  15779886
KLDRERAKN103-111 A*0301  15779886
KNWPFLEGC23-31 A*0201  15779886
KQFEELTLG91-99 A*0201  15779886
KQFEELTLG91-99 B*1501  15779886
KVRRAIEQL130-138 A*0201  15779886
KVRRAIEQL130-138 A*2402  15779886
KVRRAIEQL130-138 B*0702  15779886
KVRRAIEQL130-138 B*0801  15779886
KVRRAIEQL130-138 B*1501  15779886
LKDHRISTF14-22 A*2402  15779886
LPPAWQPFL6-14 A*0201  15779886
LPPAWQPFL6-14 A*2402  15779886
LPPAWQPFL6-14 B*0702  15779886
LTLGEFLKL96-104 A*0201  15779886
LTLGEFLKL96-104 A*1101  15779886
LTLGEFLKL96-104 A*2402  15779886
MAEAGFIHC38-46 A*0201  15779886
MGAPTLPPA1-9 A*0201  15779886
MGAPTLPPA1-9 A*1101  15779886
NEPDLAQCF50-58 A*2402  15779886
PDLAQCFFC52-60 A*0301  15779886
PDLAQCFFC52-60 A*1101  15779886
PDLAQCFFC52-60 A*2402  15779886
PFLEGCACT26-34 A*0201  15779886
PFLKDHRIS12-20 A*2402  15779886
PPAWQPFLK7-15 A*0301  15779886
PPAWQPFLK7-15 A*1101  15779886
QCFFCFKEL56-64 A*2402  15779886
QPFLKDHRI11-19 B*0702  15779886
QPFLKDHRI11-19 B*0801  15779886
RAIEQLAAM133-141 A*0201  15779886
RAIEQLAAM133-141 A*1101  15779886
RAIEQLAAM133-141 A*2402  15779886
RAIEQLAAM133-141 B*0702  15779886
RAIEQLAAM133-141 B*1501  15779886
RISTFKNWP18-26 A*0201  15779886
RMAEAGFIH37-45 A*0201  15779886
RMAEAGFIH37-45 A*0301  15779886
RMAEAGFIH37-45 A*1101  15779886
RMAEAGFIH37-45 A*2402  15779886
RMAEAGFIH37-45 B*1501  15779886
SGCAFLSVK82-90 A*0301  15779886
SGCAFLSVK82-90 A*1101  15779886
SSGCAFLSV81-89 A*0201  15779886
SSGCAFLSV81-89 A*2402  15779886
STFKNWPFL20-28 A*0201  15779886
STFKNWPFL20-28 A*0301  15779886
STFKNWPFL20-28 A*1101  15779886
STFKNWPFL20-28 A*2402  15779886
SVKKQFEEL88-96 A*0201  15779886
SVKKQFEEL88-96 A*2402  15779886
SVKKQFEEL88-96 B*0702  15779886
SVKKQFEEL88-96 B*0801  15779886
SVKKQFEEL88-96 B*1501  15779886
TLGEFLKLD97-105 A*0201  15779886
TLGEFLKLD97-105 A*2402  15779886
TLPPAWQPF5-13 A*0201  15779886
TLPPAWQPF5-13 A*2402  15779886
TLPPAWQPF5-13 B*1501  15779886
WPFLEGCAC25-33 A*2402  15779886
WPFLEGCAC25-33 B*0702  15779886
Predicted HLA binders
Allele:  predictions
Peptide length:   
Antigen sequenceMGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPD
DDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAEKVRRAIEQLAA
MD