Antigen Record Ag001870

AgACCAg001870
Date04-08-2008
Last updated14-12-2016
Antigen NameFOLH1
Common NameProstate-specific membrane antigen
Full NameFolate hydrolase 1
SynonymFolylpoly-gamma- glutamate carboxypeptidase,Glutamate carboxypeptidase 2; Glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; N- acetylated-alpha-linked acidic dipeptidase I; N-acetylated alpha-linked acidic dipeptidase 1; NAALADase I; Prostate- specific membrane antigen; Pteroylpoly-gamma-glutamate carboxypeptidase; folate hydrolase (prostate-specific membrane antigen) 1; folate hydrolase 1 (prostate-specific membrane antigen); folylpoly-gamma-glutamate carboxypeptidase; glutamate carboxylase II; prostate-specific membrane antigen; EC 3.4.17.21; FGCP; FOLH1; GCP2; GCPII; NAALAD1, NAALAdase, PSM, PSMA, mGCP

another display format
  • Folylpoly-gamma- glutamate carboxypeptidase,Glutamate carboxypeptidase 2
  • Glutamate carboxypeptidase II
  • Membrane glutamate carboxypeptidase
  • N- acetylated-alpha-linked acidic dipeptidase I
  • N-acetylated alpha-linked acidic dipeptidase 1
  • NAALADase I
  • Prostate- specific membrane antigen
  • Pteroylpoly-gamma-glutamate carboxypeptidase
  • folate hydrolase (prostate-specific membrane antigen) 1
  • folate hydrolase 1 (prostate-specific membrane antigen)
  • folylpoly-gamma-glutamate carboxypeptidase
  • glutamate carboxylase II
  • prostate-specific membrane antigen
  • EC 3.4.17.21
  • FGCP
  • FOLH1
  • GCP2
  • GCPII
  • NAALAD1, NAALAdase, PSM, PSMA, mGCP
UniProt IDA4UU12
NCBI Gene ID2346
GeneCard IDGC11M051622
AnnotationThis is a full length sequence.
IsoformsAg000175,  Ag000176,  Ag000177,  Ag000178,  Ag000179,  Ag000180,  Ag001867,  Ag001868,  Ag001869,  Ag001871

Alignment of all Isoforms
Mutation entriesAg003570,  Ag003571,  Ag003572

View mutation map
RNA/protein expression profileRNA and protein Expression profile
T cell epitopeEpitope sequencePositionHLA alleleReference
KVFRGNKVK192-200 A*1101  16203785
KVFRGNKVK192-200 A*3101  16203785
KVFRGNKVK192-200 A*3301  16203785
LYSDPADYF212-220 A24  12473604
NYARTEDFF163-171 A24  12473604
NYTLRVDCTPLMYSL444-458 DRB1*0401  12960111
Predicted HLA binders
Allele:  predictions
Peptide length:   
Antigen sequenceMTAGSSYPLFLAAYACTGCLAERLGWFIKSSNEATNITPKHNMKAFLDELKAENIKKFLYNFTQIPHLAG
TEQNFQLAKQIQSQWKEFGLDSVELAHYDVLLSYPNKTHPNYISIINEDGNEIFNTSLFEPPPPGYENVS
DIVPPFSAFSPQGMPEGDLVYVNYARTEDFFKLERDMKINCSGKIVIARYGKVFRGNKVKNAQLAGAKGV
ILYSDPADYFAPGVKSYPDGWNLPGGGVQRGNILNLNGAGDPLTPGYPANEYAYRRGIAEAVGLPSIPVH
PIGYYDAQKLLEKMGGSAPPDSSWRGSLKVPYNVGPGFTGNFSTQKVKMHIHSTNEVTRIYNVIGTLRGA
VEPDRYVILGGHRDSWVFGGIDPQSGAAVVHENVRSFGTLKKEGWRPRRTILFASWDAEEFGLLGSTEWA
EENSRLLQERGVAYINADSSIEGNYTLRVDCTPLMYSLVHNLTKELKSPDEGFEGKSLYESWTKKSPSPE
FSGMPRISKLGSGNDFEVFFQRLGIASGRARYTKNWETNKFSGYPLYHSVYETYELVEKFYDPMFKYHLT
VAQVRGGMVFELANSIVLPFDCRDYAVVLRKYADKIYSISMKHPQEMKTYSVSFDSLFSAVKNFTEIASK
FSERLQDFDKSKHVIYAPSSHNKYAGESFPGIYDALFDIESKVDPSKAWGEVKRQIYVAAFTVQAAAETL
SEVA