Antigen Record Ag000171

AgACCAg000171
Date11-02-2007
Last updated20-12-2016
Antigen NameCTAG2
Common NameNY-ESO-ORF2 or LAGE-1
Full NameCTL-recognized antigen on melanoma
SynonymESO-2 protein; Human autoimmunogenic cancer/testis antigen NY-ESO-1 mRNA, complete cds; L antigen family member 1; LAGE-1 protein; LAGE-1a protein transcript variant 1; LAGE-1a protein transcript variant 2; cancer/testis antigen 2; CAMEL; ESO2; LAGE-1; LAGE-2b; LAGE1; MGC138724; MGC3803

another display format
  • ESO-2 protein
  • Human autoimmunogenic cancer/testis antigen NY-ESO-1 mRNA, complete cds
  • L antigen family member 1
  • LAGE-1 protein
  • LAGE-1a protein transcript variant 1
  • LAGE-1a protein transcript variant 2
  • cancer/testis antigen 2
  • CAMEL
  • ESO2
  • LAGE-1
  • LAGE-2b
  • LAGE1
  • MGC138724
  • MGC3803
UniProt IDO75638
NCBI Gene ID30848
GeneCard IDGC0XM154651
CommentThis is a splice isoform.
AnnotationThis is a full length sequence.
IsoformsAg000170,  Ag003567

Alignment of all Isoforms
Mutation entriesAg003567,  Ag003568,  Ag003569

View mutation map
RNA/protein expression profileRNA and protein Expression profile
T cell epitopeEpitope sequencePositionHLA alleleReference
AADHRQLQLSISSCLQQL139-156 DRB1*0101  10684854
AADHRQLQLSISSCLQQL139-156 DRB1*0102  10684854
AADHRQLQLSISSCLQQL139-156 DRB1*0103  10684854
AADHRQLQLSISSCLQQL139-156 DR4  10684854
AADHRQLQLSISSCLQQL139-156 DRB4*0103  10684854
AGATGGRGPRGAGA37-50 DR15  16551878
QLSLLMWIT155-163 A2  9432985
QLSLLMWITQCFL155-167 A2  11970981
SLLMWITQC157-165 A2  9432985
SLLMWITQCFL157-167 A2  9432985
SLLMWITQCFLPVF157-170 DP4  11259659
ELVRRILSR103-111 A68  16187088
ILSRDAAPLPRPG108-120 DR13  15728473
Predicted HLA binders
Allele:  predictions
Peptide length:   
Antigen sequenceMQAEGRGTGGSTGDADGPGGPGIPDGPGGNAGGPGEAGATGGRGPRGAGAARASGPRGGAPRGPHGGAAS
AQDGRCPCGARRPDSRLLELHITMPFSSPMEAELVRRILSRDAAPLPRPGAVLKDFTVSGNLLFIRLTAA
DHRQLQLSISSCLQQLSLLMWITQCFLPVFLAQAPSGQRR