Antigen Record Ag001749

AgACCAg001749
Date04-08-2008
Last updated14-12-2016
Antigen NameMAGEA3
Common NameMAGE-A3
Full NameMelanoma-associated antigen 3
SynonymAntigen MZ2-D; MAGE-3 antigen; melanoma antigen family A, 3; Melanoma antigen, family A, 3; HIP8; HYPD; MAGE3; MGC14613; MAGEA3; MAGE-A3

another display format
  • Antigen MZ2-D
  • MAGE-3 antigen
  • melanoma antigen family A, 3
  • Melanoma antigen, family A, 3
  • HIP8
  • HYPD
  • MAGE3
  • MGC14613
  • MAGEA3
  • MAGE-A3
UniProt IDQ53EX0
NCBI Gene ID4102
GeneCard IDGC0XP152698
AnnotationThis is a full length sequence.
IsoformsAg000028

Alignment of all Isoforms
Mutation entriesAg002171

View mutation map
RNA/protein expression profileRNA and protein Expression profile
T cell epitopeEpitope sequencePositionHLA alleleReference
FLLLKYRAREPVTKAE119-134 DRB1*1301  10049940
FLLLKYRAREPVTKAE119-134 DRB1*1302  10049940
LLKYRAREPVTKAE121-134 DRB1*1301  10049940
LLKYRAREPVTKAE121-134 DRB1*1302  10049940
REPVTKAEML127-136 B37  11260504
REPVTKAEML127-136 B*3701  11260504
LLKYRAREPVTKAE121-134 DRB1  10453041 28025978
EGDCAPEEK212-220 Cw7  14764691
LVHFLLLKY116-124 A*0201  15905511
ACYEFLWGPRALVETS267-282 DR1  12817001
AELVHFLLL114-122 B40  11854353
AELVHFLLLKYRAR114-127 DRB1*1301  10049940
AELVHFLLLKYRAR114-127 DRB1*1302  10049940
EVDPIGHLY168-176 A1  10453041
EVDPIGHLY168-176 B*3501  10453041
FLWGPRALV271-279 A*0201  9278345 11441084
FLWGPRALV271-279 A*0202  11441084
FLWGPRALV271-279 A*0203  11441084
FLWGPRALV271-279 A*0206  11441084
FLWGPRALV271-279 A*0207  9278345
FLWGPRALV271-279 A*0209  9278345
FLWGPRALV271-279 A*6802  11441084
GDNQIMPKAGLLIIV191-205 DR1  12393675
GDNQIMPKAGLLIIV191-205 DR4  12393675
GDNQIMPKAGLLIIV191-205 DR11  12393675
IMPKAGLLI195-203 A24  9377553
IMPKAGLLIIV195-205 A2  9862732
IMPKAGLLIIV195-205 A*0201  11441084
IMPKAGLLIIV195-205 A*0202  11441084
IMPKAGLLIIV195-205 A*0203  11441084
IMPKAGLLIIV195-205 A*0206  11441084
KIWEELSVL220-228 A*0201  11441084
KIWEELSVL220-228 A*0202  11441084
KIWEELSVL220-228 A*0206  11441084
KKLLTQHFVQENYLEY243-258 DP4  11103782
KKLLTQHFVQENYLEY243-258 DQ6  11103782
KVAELVHFL112-120 A2  9544234
KVAELVHFL112-120 A*0201  11441084
KVAELVHFL112-120 A*0202  11441084
KVAELVHFL112-120 A*0203  11441084
KVAELVHFL112-120 A*0206  11441084
KVAELVHFL112-120 A*6802  11441084
LLKYRAREPVTKAEMLGSVVGNWQ121-144 DRB1*0401  12631591
LVFGIELMEV160-169 A*0201  11441084
LVFGIELMEV160-169 A*0202  11441084
LVFGIELMEV160-169 A*0203  11441084
LVFGIELMEV160-169 A*0206  11441084
LVFGIELMEV160-169 A*6802  11441084
MEVDPIGHLY167-176 B18  12366779
MEVDPIGHLY167-176 B44  12366779
MEVDPIGHLY167-176 B*4402  12366779
MEVDPIGHLY167-176 B*4403  12366779
QLVFGIELMEV159-169 A2  9862732
QLVFGIELMEV159-169 A*0201  11441084
QLVFGIELMEV159-169 A*0202  11441084
QLVFGIELMEV159-169 A*0203  11441084
QLVFGIELMEV159-169 A*0206  11441084
QLVFGIELMEV159-169 A*6802  11441084
RKVAELVHFLLLKYR111-125 DR1  12393675
RKVAELVHFLLLKYR111-125 DPB1*04  20857101
RKVAELVHFLLLKYR111-125 DR4  20857101
RKVAELVHFLLLKYR111-125 DR11  12393675
RKVAELVHFLLLKYRA111-126 DRB1*1301  10049940
SSLQLVFGIELMEVD156-170 DRB1*07  17628799
TFPDLESEF97-105 A*2402  10209953
TQHFVQENYLEY247-258 DPB1*0401  11103782
TQHFVQENYLEY247-258 DPB1*0402  11103782
TSYVKVLHHMVKISG281-295 DR1  12393675
TSYVKVLHHMVKISG281-295 DR4  12393675
TSYVKVLHHMVKISG281-295 DR11  12393675
VAELVHFLL113-121 A24  16446550
VFGIELMEVDPIGHL161-175 DRB1*07  17628799
VFGIELMEVDPIGHL161-175 DRB4*01  17628799
WQYFFPVIF143-151 B52  10681453
YRAREPVTKAEMLG124-137 DRB1*0401  12631591
Predicted HLA binders
Allele:  predictions
Peptide length:   
Antigen sequenceMPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASS
LPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVV
GNWQYFFPVIFSKAFSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIA
REGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVE
TSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE