Antigen Record Ag000324

AgACCAg000324
Date11-02-2007
Last updated14-12-2016
Antigen NameLCK
Common NameLck
Full NameLymphocyte cell-specific protein-tyrosine kinase
SynonymProto-oncogene tyrosine-protein kinase LCK; T cell- specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; lymphocyte-specific protein tyrosine kinase; p56(LSTRA) protein-tyrosine kinase; EC 2.7.10.2; LSK; YT16; p56-LCK; p56lck; pp58lck; LCK

another display format
  • Proto-oncogene tyrosine-protein kinase LCK
  • T cell- specific protein-tyrosine kinase
  • T-lymphocyte specific protein tyrosine kinase p56lck
  • lymphocyte-specific protein tyrosine kinase
  • p56(LSTRA) protein-tyrosine kinase
  • EC 2.7.10.2
  • LSK
  • YT16
  • p56-LCK
  • p56lck
  • pp58lck
  • LCK
UniProt IDP06239
NCBI Gene ID3932
GeneCard IDGC01P032251
CommentThis is a splice isoform.
AnnotationThis is a full length sequence.
IsoformsAg000322,  Ag000323,  Ag001979

Alignment of all Isoforms
Mutation entriesAg003855,  Ag003856,  Ag003857

View mutation map
RNA/protein expression profileRNA and protein Expression profile
T cell epitopeEpitope sequencePositionHLA alleleReference
DYLRSVLEDF518-527 A*2402  11180095
HYTNASDGL208-216 A*2402  11180095
ILEQSGEWWK90-99 A11  18043580
ILEQSGEWWK90-99 A31  18043580
ILEQSGEWWK90-99 A33  18043580
IQNLERGYR480-488 A11  18043580
IQNLERGYR480-488 A31  18043580
IQNLERGYR480-488 A33  18043580
TFDYLRSVL516-524 A*2402  11180095
VIQNLERGYR479-488 A11  18043580
VIQNLERGYR479-488 A31  18043580
VIQNLERGYR479-488 A33  18043580
Predicted HLA binders
Allele:  predictions
Peptide length:   
Antigen sequenceMGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVTYEGSNPPASPLQDNLVIALH
SYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQ
LLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLHELVRHYT
NASDGLCTRLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSM
SPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENDTLLDSQLEEKGLGASPWGNLGQQLLLLP
TGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIE
DNEYTAREGAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMV
RPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP