Antigen Record Ag000009

AgACCAg000009
Date11-02-2007
Last updated14-12-2016
Antigen NameCEACAM5
Common NameCEA
Full NameCarcinoembryonic antigen-related cell adhesion molecule
SynonymCEA; 5CD66e antigen; Carcinoembryonic antigen; Carcinoembryonic antigen-related cell adhesion molecule 5 precursor; Meconium antigen 100; CD66e; CEA; DKFZp781M239

another display format
  • CEA
  • 5CD66e antigen
  • Carcinoembryonic antigen
  • Carcinoembryonic antigen-related cell adhesion molecule 5 precursor
  • Meconium antigen 100
  • CD66e
  • CEA
  • DKFZp781M239
UniProt IDP06731
NCBI Gene ID1048
GeneCard IDGC19P041709
AnnotationThis is a full length sequence.
IsoformsAg001733,  Ag001734,  Ag001735

Alignment of all Isoforms
Mutation entriesAg002170,  Ag002183,  Ag002184,  Ag002185

View mutation map
RNA/protein expression profileRNA and protein Expression profile
T cell epitopeEpitope sequencePositionHLA alleleReference
ATVGIMIGV687-695 A*0201  11441084
ATVGIMIGV687-695 A*0202  11441084
ATVGIMIGV687-695 A*0203  11441084
ATVGIMIGV687-695 A*0206  11441084
ATVGIMIGV687-695 A*6802  11441084
AYVCGIQNSVSANRS568-582 DR3  16585607
DTGFYTLHVIKSDLVNEEATGQFRV116-140 DR4  14624313
EIIYPNASLLIQN99-111 DR7  16585607
EIIYPNASLLIQN99-111 DR14  14679013
GVLVGVALI693-702 A*0201  10940913
HLFGYSWYK61-69 A3  9927058
HLFGYSWYK61-69 A*1101  9927058
IMIGVLVGV691-699 A2  9544234 11441084
IMIGVLVGV691-699 A*0202  11441084
IMIGVLVGV691-699 A*0203  11441084
IMIGVLVGV691-699 A*0206  11441084
IMIGVLVGV691-699 A*6802  11441084
IPQQHTQVL632-640 B*0702  11016651
LWWVNNQSLPVSP177-189,  355-367 DRB1*0405  14679013
LWWVNNQSLPVSP177-189,  355-367 DRB1*1101  14679013
LWWVNNQSLPVSP177-189,  355-367 DRB1*1104  14679013
LWWVNNQSLPVSP177-189,  355-367 DR3  14679013
LWWVNNQSLPVSP177-189,  355-367 DR7  14679013
LWWVNNQSLPVSP177-189,  355-367 DR13  14679013
LWWVNNQSLPVSP177-189,  355-367 DR14  14679013
NSIVKSITVSASG666-678 DR14  16585607
QYSWFVNGTF268-277 A24  9935237
TYACFVSNL652-660 A*2402  9935237
TYYRPGVNLSLSC425-437 DR7  16585607
YACFVSNLATGRNNS653-667 DR9  12374692
YLSGANLNL605-613 A*0201  11441084
YLSGANLNL605-613 A*0202  11441084
YLSGANLNL605-613 A*0203  11441084
YLWWVNNQSL176-185,  354-363 A*0201  11441084
YLWWVNNQSL176-185,  354-363 A*0202  11441084
YLWWVNNQSL176-185,  354-363 A*0203  11441084
YLWWVNNQSL176-185,  354-363 A*0206  11441084
YLWWVNNQSL176-185,  354-363 A*6802  11441084
YSWRINGIPQQHTQV625-639 DR4  15102695
HLA ligandLigand SequencePositionHLA alleleReference
ELFISNITEK461-470 A*0301  8574469
FISNITEK463-470 A*0301  8574469
FVSNLATGR656-664 A*0301  8574469
HLFGYSWY61-68 A*0301  8574469
HLFGYSWYK61-69 A*0301  9927058
HLFGYSWYK61-69 A*3101  9927058
HLFGYSWYK61-69 A*3301  9927058
HLFGYSWYK61-69 A*6801  9927058
KITPNNNGTY644-653 A*0301  8574469
LFISNITEK462-470 A*0301  8574469
NLPQHLFGY57-65 A*0301  8574469
QIIGYVIGT78-86 A*0201  11441084
QIIGYVIGT78-86 A*0202  11441084
QIIGYVIGT78-86 A*0203  11441084
QIIGYVIGT78-86 A*0206  11441084
QIIGYVIGT78-86 A*6802  11441084
RINGIPQQH628-636 A*0301  9927058
RLQLSNDNR368-376 A*0301  8574469
RLQLSNGNR190-198,  546-554 A*0301  9927058
RTLTLFNVTR198-207,  554-563 A*0301  9927058
RVDGNRQIIGY72-82 A*0301  8574469
RVYPELPK139-146 A*0301  8574469
TISPLNTSY241-249 A*0301  8574469
TISPSYTYY419-427 A*0301  8574469
TITVSAELPK493-502 A*0301  8574469
TITVYAEPPK315-324 A*0301  8574469
TLFNVTRNDAR557-567 A*0301  8574469
TLTLFNVTR199-207,  555-563 A*0301  8574469
TVSAELPK495-502 A*0301  8574469
TVYAEPPK317-324 A*0301  8574469
Predicted HLA binders
Allele:  predictions
Peptide length:   
Antigen sequenceMESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKG
ERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRV
YPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDT
ASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQS
TQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQ
NTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNELSVDHSDPVILNVLYGPDDPTI
SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTT
VKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFN
VTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRIN
GIPQQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVA
LI