Epstein-Barr virus T cell antigen database

Epstein-Barr virus (EBV) T cell antigen database is a data source and analysis platform for EBV immune target discovery by focusing on EBV antigens that contain HLA ligands and T cell epitopes.

The Database facilitates

User keyword to search for viral sequence entries.
User keyword to search for T-cell epitopes.
BLAST against the database
Multiple sequence alignment
Visualization of T cell epitopes
Sequence variability analysis
Real time prediction of HLA binding peptides (accessible through individual records)
Conservation analysis of experimentally validated T cell epitopes and predicted HLA binders

For details of the system, please refer to the paper below:
Zhang,G.L., Keskin,D., Chitkushev,L., Reinherz,E., Brusic,V. EBVdb: a data repository and analysis platform for knowledge discovery in Epstein-Barr virus with applications in T cell immunotherapy.. ICSI3 2015, July 17-18, Taomina, Italy.

Developed by Bioinformatics Core at Cancer Vaccine Center, Dana-Farber Cancer Institute.