TANTIGEN 2.0: Tumor T-cell Antigen Database

Tumor T cell antigen database is a data source and analysis platform for cancer vaccine target discovery focusing on human tumor antigens that contain HLA ligands and T cell epitopes. It catalogs more than 1000 tumor peptides from 292 different proteins. The database also provides information on T cell epitopes and HLA ligands with full references, gene expression profiles, antigen isoforms, and mutations. Predicted binding peptides of 15 HLA Class I and Class II alleles were also included in the database.

TANTIGEN facilitates

For details of the system, please refer to the paper below:
Olsen LR, Tongchusak S, Lin H, Reinherz EL, Brusic V, Zhang GL. (2017) TANTIGEN: a comprehensive database of tumor T cell antigens. Cancer Immunol Immunother. doi: 10.1007/s00262-017-1978-y.
TANTIGEN version 1.0, Dec 1, 2009. Developed by Bioinformatics Core at Cancer Vaccine Center, Dana-Farber Cancer Institute.